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P2RY6 蛋白

P2RY6 宿主: 人 宿主: Mammalian Cells Synthetic Nanodisc
产品编号 ABIN7538503
发货至: 中国
  • 抗原 See all P2RY6 蛋白
    P2RY6 (Pyrimidinergic Receptor P2Y, G-Protein Coupled, 6 (P2RY6))
    蛋白类型
    Synthetic Nanodisc
    宿主
    • 4
    • 1
    资源
    • 3
    • 2
    Mammalian Cells
    原理
    Human P2RY6 full length protein-synthetic nanodisc
    产品特性
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
    Top Product
    Discover our top product P2RY6 蛋白
  • 说明

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    P2RY6 (Pyrimidinergic Receptor P2Y, G-Protein Coupled, 6 (P2RY6))
    别名
    P2RY6 (P2RY6 产品)
    别名
    P2Y6 Protein, 2010204J23Rik Protein, P2y6 Protein, P2RY3 Protein, P2Y3 Protein, P2Y6R Protein, pyrimidinergic receptor P2Y6 Protein, pyrimidinergic receptor P2Y, G-protein coupled, 6 Protein, P2RY6 Protein, P2ry6 Protein
    背景
    The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, which is a G-protein coupled receptor, is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. It is proposed that this receptor mediates inflammatory responses. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Mar 2013]
    分子量
    The human full length P2RY6 protein has a MW of 36.4kDa
    UniProt
    Q15077
    途径
    Smooth Muscle Cell Migration
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