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P2RY1 蛋白

P2RY1 宿主: 人 宿主: Mammalian Cells Synthetic Nanodisc
产品编号 ABIN7538493
发货至: 中国
  • 抗原 See all P2RY1 蛋白
    P2RY1 (Purinergic Receptor P2Y, G-Protein Coupled, 1 (P2RY1))
    蛋白类型
    Synthetic Nanodisc
    宿主
    • 5
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    资源
    • 2
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    Mammalian Cells
    原理
    Human P2RY1 full length protein-synthetic nanodisc
    产品特性
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
    Top Product
    Discover our top product P2RY1 蛋白
  • 说明

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    P2RY1 (Purinergic Receptor P2Y, G-Protein Coupled, 1 (P2RY1))
    别名
    P2RY1 (P2RY1 产品)
    别名
    P2Y1 Protein, P2y Protein, P2y1 Protein, purinergic receptor P2Y, G-protein coupled 1 Protein, purinergic receptor P2Y1 Protein, P2ry1 Protein, P2RY1 Protein
    背景
    The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq, Jul 2008]
    分子量
    The human full length P2RY1 protein has a MW of 42.1kDa
    UniProt
    P47900
    途径
    Regulation of Carbohydrate Metabolic Process, Feeding Behaviour
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