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CD45 Protein (AA 26-566) (His tag)

PTPRC 宿主: 小鼠 宿主: Mammalian Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN7538492
发货至: 中国
  • 抗原 See all CD45 (PTPRC) 蛋白
    CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))
    蛋白类型
    Recombinant
    产品特性
    AA 26-566
    宿主
    • 20
    • 10
    • 3
    • 1
    小鼠
    资源
    • 12
    • 8
    • 6
    • 3
    • 2
    • 2
    • 1
    Mammalian Cells
    标记
    This CD45 protein is labelled with His tag.
    原理
    Recombinant mouse CD45 protein with C-terminal 6xHis tag
    特异性
    Mouse CD45 (Gln26-Lys566) 6xHis tag
    产品特性
    Extracellular Domain Protein
    纯化方法
    Purified from cell culture supernatant by affinity chromatography
    纯度
    The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product PTPRC 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))
    别名
    CD45 (PTPRC 产品)
    别名
    PTPRC Protein, si:dkeyp-47c5.1 Protein, B220 Protein, CD45 Protein, CD45R Protein, GP180 Protein, L-CA Protein, LCA Protein, LY5 Protein, T200 Protein, Cd45 Protein, Ly-5 Protein, Lyt-4 Protein, loc Protein, Lca Protein, RT7 Protein, cd45 Protein, protein tyrosine phosphatase, receptor type C Protein, protein tyrosine phosphatase, receptor type, C Protein, receptor-type tyrosine-protein phosphatase C Protein, PTPRC Protein, ptprc Protein, LOC100074271 Protein, Ptprc Protein
    背景
    Enables several functions, including heparan sulfate proteoglycan binding activity, heparin binding activity, and protein tyrosine phosphatase activity. Involved in several processes, including lymphocyte differentiation, positive regulation of macromolecule metabolic process, and regulation of signal transduction. Acts upstream of or within several processes, including lymphocyte differentiation, positive regulation of lymphocyte activation, and regulation of protein phosphorylation. Located in external side of plasma membrane, focal adhesion, and membrane raft. Is expressed in several structures, including 3rd branchial arch, alimentary system, cardiovascular system, hemolymphoid system, and placenta. Used to study systemic lupus erythematosus. Human ortholog(s) of this gene implicated in hepatitis C, multiple sclerosis, severe combined immunodeficiency, and severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, Nk cell-positive. Orthologous to human PTPRC (protein tyrosine phosphatase receptor type C). [provided by Alliance of Genome Resources, Apr 2022]
    分子量
    predicted molecular mass of 59.5 kDa after removal of the signal peptide. The apparent molecular mass of mCD45-His is 130-250 kDa due to glycosylation.
    UniProt
    P06800
    途径
    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, BCR Signaling
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