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PTGER1 蛋白

PTGER1 宿主: 人 宿主: Mammalian Cells Synthetic Nanodisc
产品编号 ABIN7538490
发货至: 中国
  • 抗原 See all PTGER1 蛋白
    PTGER1 (Prostaglandin E Receptor 1 (Subtype EP1), 42kDa (PTGER1))
    蛋白类型
    Synthetic Nanodisc
    宿主
    • 3
    • 1
    资源
    • 2
    • 1
    • 1
    Mammalian Cells
    原理
    Human PE2R1 full length protein-synthetic nanodisc
    产品特性
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
    Top Product
    Discover our top product PTGER1 蛋白
  • 说明

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    PTGER1 (Prostaglandin E Receptor 1 (Subtype EP1), 42kDa (PTGER1))
    别名
    PE2R1 (PTGER1 产品)
    别名
    EP1 Protein, PTGER1 Protein, 42kDa Protein, Ptgerep1 Protein, prostaglandin E receptor 1 Protein, prostaglandin E receptor 1 (subtype EP1), 42kDa Protein, prostaglandin E receptor 1 (subtype EP1) Protein, PTGER1 Protein, Ptger1 Protein
    背景
    The protein encoded by this gene is a member of the G protein-coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). Through a phosphatidylinositol-calcium second messenger system, G-Q proteins mediate this receptor's activity. Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure. Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin. [provided by RefSeq, Jul 2008]
    分子量
    The human full length PE2R1 protein has a MW of 41.8kDa
    UniProt
    P34995
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