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PTGDR 蛋白

PTGDR 宿主: 人 宿主: Mammalian Cells Synthetic Nanodisc
产品编号 ABIN7538489
发货至: 中国
  • 抗原 See all PTGDR 蛋白
    PTGDR (Prostaglandin D2 Receptor (PTGDR))
    蛋白类型
    Synthetic Nanodisc
    宿主
    • 3
    • 1
    资源
    • 2
    • 2
    Mammalian Cells
    原理
    Human PD2R full length protein-synthetic nanodisc
    产品特性
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
    Top Product
    Discover our top product PTGDR 蛋白
  • 说明

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    PTGDR (Prostaglandin D2 Receptor (PTGDR))
    别名
    PD2R (PTGDR 产品)
    别名
    AS1 Protein, ASRT1 Protein, DP Protein, DP1 Protein, PTGDR1 Protein, Ptgdr Protein, Ptgdr2 Protein, PTGDR Protein, PGD Protein, prostaglandin D2 receptor Protein, prostaglandin D receptor Protein, PTGDR Protein, Ptgdrl Protein, Ptgdr Protein
    背景
    This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein is reported to be a receptor for prostaglandin D2, which is a mediator of allergic inflammation and allergic airway inflammation in asthma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
    分子量
    The human full length PD2R protein has a MW of 40.3kDa
    UniProt
    Q13258
    途径
    Thromboxane A2 Receptor Signaling
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