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- 抗原 See all PLA2R1 蛋白
- PLA2R1 (phospholipase A2 Receptor 1, 180kDa (PLA2R1))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human PLA2R1 full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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phospholipase A2 Receptor 1, 180kDa (PLA2R1) (AA 1097-1246), (AA 21-164), (AA 223-359) protein (His tag)
PLA2R1 宿主: 人 宿主: Mammalian Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
phospholipase A2 Receptor 1, 180kDa (PLA2R1) (AA 1097-1246), (AA 21-521) protein (His tag)PLA2R1 宿主: 人 宿主: Mammalian Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
phospholipase A2 Receptor 1, 180kDa (PLA2R1) (AA 21-1397) protein (His tag)PLA2R1 宿主: 人 宿主: Mammalian Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
phospholipase A2 Receptor 1, 180kDa (PLA2R1) (AA 21-164) protein (Fc Tag)PLA2R1 宿主: 人 宿主: Mammalian Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- PLA2R1 (phospholipase A2 Receptor 1, 180kDa (PLA2R1))
- 别名
- PLA2R1 (PLA2R1 产品)
- 别名
- Pla2-r Protein, Pla2g1br Protein, Pla2r Protein, CLEC13C Protein, PLA2-R Protein, PLA2G1R Protein, PLA2IR Protein, PLA2R Protein, phospholipase A2 receptor 1 Protein, PLA2R1 Protein, Pla2r1 Protein
- 背景
- This protein is a phospholipase A2 receptor. The protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified.
- 分子量
- The human full length PLA2R1 protein has a MW of 168.6 kDa
- UniProt
- Q13018
- 途径
- Positive Regulation of Response to DNA Damage Stimulus
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