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PTH2R 蛋白

PTH2R 宿主: 人 宿主: Mammalian Cells Synthetic Nanodisc
产品编号 ABIN7538469
发货至: 中国
  • 抗原 See all PTH2R 蛋白
    PTH2R (Parathyroid Hormone 2 Receptor (PTH2R))
    蛋白类型
    Synthetic Nanodisc
    宿主
    • 3
    • 1
    资源
    • 3
    • 1
    Mammalian Cells
    原理
    Human PTH2R full length protein-synthetic nanodisc
    产品特性
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
    Top Product
    Discover our top product PTH2R 蛋白
  • 说明

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    PTH2R (Parathyroid Hormone 2 Receptor (PTH2R))
    别名
    PTH2R (PTH2R 产品)
    别名
    PTHR2 Protein, pthr2 Protein, zgc:123155 Protein, Pthr2 Protein, parathyroid hormone 2 receptor Protein, si:dkeyp-4h4.1 Protein, PTH2R Protein, pth2r Protein, Pth2r Protein, si:dkeyp-4h4.1 Protein
    背景
    The protein encoded by this gene is a member of the G-protein coupled receptor 2 family. This protein is a receptor for parathyroid hormone (PTH). This receptor is more selective in ligand recognition and has a more specific tissue distribution compared to parathyroid hormone receptor 1 (PTHR1). It is activated only by PTH and not by parathyroid hormone-like hormone (PTHLH) and is particularly abundant in brain and pancreas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
    分子量
    The human full length PTH2R protein has a MW of 62.2kDa
    UniProt
    P49190
    途径
    cAMP Metabolic Process
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