OPRK1 蛋白
OPRK1
宿主: 人
宿主: Mammalian Cells
Synthetic Nanodisc
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- 抗原 See all OPRK1 蛋白
- OPRK1 (Opioid Receptor, kappa 1 (OPRK1))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human OPRK full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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- Discover our top product OPRK1 蛋白
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Opioid Receptor, kappa 1 (OPRK1) (AA 1-58) protein (GST tag)
OPRK1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- OPRK1 (Opioid Receptor, kappa 1 (OPRK1))
- 别名
- OPRK (OPRK1 产品)
- 别名
- OPRK1 Protein, LOC780448 Protein, kor Protein, KOR Protein, OPRK Protein, K-OR-1 Protein, KOR-1 Protein, MSL-1 Protein, Oprk2 Protein, R21 Protein, opioid receptor, kappa 1 Protein, opioid receptor kappa 1 Protein, oprk1 Protein, OPRK1 Protein, Oprk1 Protein
- 背景
- This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017]
- 分子量
- The human full length OPRK protein has a MW of 42.6kDa
- UniProt
- P41145
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