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NTSR2 蛋白

NTSR2 宿主: 人 宿主: Mammalian Cells Synthetic Nanodisc
产品编号 ABIN7538411
发货至: 中国
  • 抗原 See all NTSR2 蛋白
    NTSR2 (Neurotensin Receptor 2 (NTSR2))
    蛋白类型
    Synthetic Nanodisc
    宿主
    • 4
    • 1
    资源
    • 2
    • 2
    • 1
    Mammalian Cells
    原理
    Human NTR2 full length protein-synthetic nanodisc
    产品特性
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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    Discover our top product NTSR2 蛋白
  • 说明

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    NTSR2 (Neurotensin Receptor 2 (NTSR2))
    别名
    NTR2 (NTSR2 产品)
    别名
    NTSR2 Protein, NTR2 Protein, NT2R Protein, NTRL Protein, neurotensin receptor 2 Protein, NTSR2 Protein, Ntsr2 Protein
    背景
    The protein encoded by this gene belongs to the G protein-coupled receptor family that activate a phosphatidylinositol-calcium second messenger system. Binding and pharmacological studies demonstrate that this receptor binds neurotensin as well as several other ligands already described for neurotensin NT1 receptor. However, unlike NT1 receptor, this gene recognizes, with high affinity, levocabastine, a histamine H1 receptor antagonist previously shown to compete with neurotensin for low-affinity binding sites in brain. These activities suggest that this receptor may be of physiological importance and that a natural agonist for the receptor may exist. [provided by RefSeq, Jul 2008]
    分子量
    The human full length NTR2 protein has a MW of 45.4kDa
    UniProt
    O95665
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