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NPY1R 蛋白

NPY1R 宿主: 人 宿主: Mammalian Cells Synthetic Nanodisc
产品编号 ABIN7538408
发货至: 中国
  • 抗原 See all NPY1R 蛋白
    NPY1R (Neuropeptide Y Receptor Y1 (NPY1R))
    蛋白类型
    Synthetic Nanodisc
    宿主
    • 5
    • 3
    • 2
    资源
    • 4
    • 3
    • 2
    Mammalian Cells
    原理
    Human NPY1R full length protein-synthetic nanodisc
    产品特性
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
    Top Product
    Discover our top product NPY1R 蛋白
  • 说明

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    NPY1R (Neuropeptide Y Receptor Y1 (NPY1R))
    别名
    NPY1R (NPY1R 产品)
    别名
    NPY1-R Protein, NPYR Protein, NPY-1 Protein, NPY1R Protein, si:dkey-253i9.3 Protein, Npyr Protein, Y1-R Protein, npy1r-A Protein, npyr Protein, neuropeptide Y receptor Y1 Protein, neuropeptide Y receptor Y1 S homeolog Protein, NPY1R Protein, Npy1r Protein, npy1r Protein, npy1r.S Protein
    背景
    This gene belongs to the G-protein-coupled receptor superfamily. The encoded transmembrane protein mediates the function of neuropeptide Y (NPY), a neurotransmitter, and peptide YY (PYY), a gastrointestinal hormone. The encoded receptor undergoes fast agonist-induced internalization through clathrin-coated pits and is subsequently recycled back to the cell membrane. Activation of Y1 receptors may result in mobilization of intracellular calcium and inhibition of adenylate cyclase activity. [provided by RefSeq, Aug 2013]
    分子量
    The human full length NPY1R protein has a MW of 44.4kDa
    UniProt
    P25929
    途径
    Negative Regulation of Hormone Secretion, Feeding Behaviour
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