NPY1R 蛋白
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- 抗原 See all NPY1R 蛋白
- NPY1R (Neuropeptide Y Receptor Y1 (NPY1R))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human NPY1R full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product NPY1R 蛋白
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- NPY1R (Neuropeptide Y Receptor Y1 (NPY1R))
- 别名
- NPY1R (NPY1R 产品)
- 别名
- NPY1-R Protein, NPYR Protein, NPY-1 Protein, NPY1R Protein, si:dkey-253i9.3 Protein, Npyr Protein, Y1-R Protein, npy1r-A Protein, npyr Protein, neuropeptide Y receptor Y1 Protein, neuropeptide Y receptor Y1 S homeolog Protein, NPY1R Protein, Npy1r Protein, npy1r Protein, npy1r.S Protein
- 背景
- This gene belongs to the G-protein-coupled receptor superfamily. The encoded transmembrane protein mediates the function of neuropeptide Y (NPY), a neurotransmitter, and peptide YY (PYY), a gastrointestinal hormone. The encoded receptor undergoes fast agonist-induced internalization through clathrin-coated pits and is subsequently recycled back to the cell membrane. Activation of Y1 receptors may result in mobilization of intracellular calcium and inhibition of adenylate cyclase activity. [provided by RefSeq, Aug 2013]
- 分子量
- The human full length NPY1R protein has a MW of 44.4kDa
- UniProt
- P25929
- 途径
- Negative Regulation of Hormone Secretion, Feeding Behaviour
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