CHRM1 蛋白
CHRM1
宿主: 人
宿主: Mammalian Cells
Synthetic Nanodisc
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- 抗原 See all CHRM1 蛋白
- CHRM1 (Muscarinic Acetylcholine Receptor M1 (CHRM1))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human ACM1 full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product CHRM1 蛋白
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Muscarinic Acetylcholine Receptor M1 (CHRM1) (AA 210-366), (Cytoplasmic Domain), (Cytosolic) protein (His tag)
CHRM1 宿主: 大鼠 宿主: 酵母菌 Recombinant > 90 % SDS
Muscarinic Acetylcholine Receptor M1 (CHRM1) (AA 210-366), (Cytoplasmic Domain), (Cytosolic) protein (His tag)CHRM1 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- CHRM1 (Muscarinic Acetylcholine Receptor M1 (CHRM1))
- 别名
- ACM1 (CHRM1 产品)
- 别名
- M1 Protein, CHRM1 Protein, HM1 Protein, M1R Protein, mAChR Protein, Chrm-1 Protein, cholinergic receptor muscarinic 1 Protein, cholinergic receptor, muscarinic 1 Protein, cholinergic receptor, muscarinic 1, CNS Protein, CHRM1 Protein, Chrm1 Protein
- 背景
- The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13. [provided by RefSeq, Jul 2008]
- 分子量
- The human full length ACM1 protein has a MW of 51.4kDa
- UniProt
- P11229
- 途径
- Synaptic Membrane
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