Melatonin Receptor 1B Protein (MTNR1B)
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- 抗原 See all Melatonin Receptor 1B (MTNR1B) 蛋白
- Melatonin Receptor 1B (MTNR1B)
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human MTR1B full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product MTNR1B 蛋白
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- Melatonin Receptor 1B (MTNR1B)
- 别名
- MTR1B (MTNR1B 产品)
- 别名
- FGQTL2 Protein, MEL-1B-R Protein, MT2 Protein, Mel1b-r Protein, Mel-1B-R Protein, MTNR1B Protein, mtnr1br Protein, MEL1B Protein, Mel1b Protein, Mt2 Protein, mel1b Protein, mtnr1b Protein, melatonin receptor 1B Protein, melatonin receptor type 1C S homeolog Protein, melatonin receptor type 1Ba Protein, MTNR1B Protein, Mtnr1b Protein, mtnr1c.S Protein, mtnr1bb Protein, mtnr1ba Protein
- 背景
- This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin. [provided by RefSeq, Jul 2008]
- 分子量
- The human full length MTR1B protein has a MW of 40.2kDa
- UniProt
- P49286
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