MC2R 蛋白
MC2R
宿主: 人
宿主: Mammalian Cells
Synthetic Nanodisc
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- 抗原 See all MC2R products
- MC2R (Melanocortin 2 Receptor (Adrenocorticotropic Hormone) (MC2R))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human ACTHR full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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Melanocortin 2 Receptor (Adrenocorticotropic Hormone) (MC2R) (AA 1-297) protein (GST tag)
MC2R 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Melanocortin 2 Receptor (Adrenocorticotropic Hormone) (MC2R) protein (Myc-DYKDDDDK Tag)MC2R 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- MC2R (Melanocortin 2 Receptor (Adrenocorticotropic Hormone) (MC2R))
- 别名
- ACTHR (MC2R 产品)
- 别名
- ACTHR Protein, ACTH-R Protein, MC2-R Protein, MC2R Protein, MC2 Protein, melanocortin 2 receptor Protein, MC2R Protein, Mc2r Protein, mc2r Protein
- 背景
- MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency. Alternate transcript variants have been found for this gene. [provided by RefSeq, May 2014]
- 分子量
- The human full length ACTHR protein has a MW of 33.9kDa
- UniProt
- Q01718
- 途径
- cAMP Metabolic Process
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