Macrophage Scavenger Receptor 1 Protein (MSR1) (AA 77-451) (His tag)
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- 抗原 See all Macrophage Scavenger Receptor 1 (MSR1) 蛋白
- Macrophage Scavenger Receptor 1 (MSR1)
- 蛋白类型
- Recombinant
- 产品特性
- AA 77-451
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宿主
- 人
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资源
- Mammalian Cells
- 标记
- This Macrophage Scavenger Receptor 1 protein is labelled with His tag.
- 原理
- Recombinant human MSR1 Protein with N-terminal 6xHis tag
- 特异性
- 6xHis tag MSR1 (Lys77-Leu451)
- 产品特性
- Extracellular Domain Protein
- 纯化方法
- Purified from cell culture supernatant by affinity chromatography
- 纯度
- The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product MSR1 蛋白
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Macrophage Scavenger Receptor 1 (MSR1) (AA 77-451) protein (His tag)
MSR1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Macrophage Scavenger Receptor 1 (MSR1) (AA 121-220) protein (GST tag)MSR1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Macrophage Scavenger Receptor 1 (MSR1) protein (His tag)MSR1 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Macrophage Scavenger Receptor 1 (MSR1) protein (Fc Tag)MSR1 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- Macrophage Scavenger Receptor 1 (MSR1)
- 别名
- MSR1 (MSR1 产品)
- 别名
- CD204 Protein, SCARA1 Protein, SR-A Protein, SRA Protein, phSR1 Protein, phSR2 Protein, MRS-A Protein, MSR Protein, MSR-A Protein, SR-AI Protein, SR-AII Protein, Scara1 Protein, Scvr Protein, MSR1 Protein, RGD1564316 Protein, macrophage scavenger receptor 1 Protein, scavenger receptor class A member 5 Protein, MSR1 Protein, Msr1 Protein, SCARA5 Protein
- 背景
- This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages. [provided by RefSeq, Jul 2008]
- 分子量
- predicted molecular mass of 42.1 kDa after removal of the signal peptide.
- UniProt
- P21757
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