EDG4 蛋白
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- 抗原 See all EDG4 (LPAR2) 蛋白
- EDG4 (LPAR2) (Lysophosphatidic Acid Receptor 2 (LPAR2))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human LPAR2 full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product LPAR2 蛋白
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- EDG4 (LPAR2) (Lysophosphatidic Acid Receptor 2 (LPAR2))
- 别名
- LPAR2 (LPAR2 产品)
- 别名
- EDG-4 Protein, EDG4 Protein, LPA-2 Protein, LPA2 Protein, lpa2 Protein, Gpbar1 Protein, Edg4 Protein, IPA2 Protein, Pbx4 Protein, RGD1561336 Protein, zgc:101053 Protein, lysophosphatidic acid receptor 2 Protein, lysophosphatidic acid receptor 2 S homeolog Protein, G protein-coupled bile acid receptor 1 Protein, growth hormone releasing hormone receptor Protein, lysophosphatidic acid receptor 2a Protein, LPAR2 Protein, lpar2.S Protein, GPBAR1 Protein, Lpar2 Protein, GHRHR Protein, lpar2a Protein
- 背景
- This gene encodes a member of family I of the G protein-coupled receptors, as well as the EDG family of proteins. This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca2 mobilization, a critical cellular response to LPA in cells, through association with Gi and Gq proteins. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]
- 分子量
- The human full length LPAR2 protein has a MW of 38.7kDa
- UniProt
- Q9HBW0
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