KIR2DL3 Protein (AA 22-245) (His tag)
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- 抗原 See all KIR2DL3 蛋白
- KIR2DL3 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3))
- 蛋白类型
- Recombinant
- 产品特性
- AA 22-245
- 宿主
- 人
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资源
- Mammalian Cells
- 标记
- This KIR2DL3 protein is labelled with His tag.
- 原理
- Recombinant Human KIR2DL3 Protein with C-terminal 6XHis tag
- 特异性
- KIR2DL3 (His22-His245) 6xHis tag
- 产品特性
- Extracellular Domain Protein
- 纯化方法
- Purified from cell culture supernatant by affinity chromatography
- 纯度
- The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product KIR2DL3 蛋白
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Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3) (AA 22-245) protein (His-Avi Tag)
KIR2DL3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3) protein (His-Avi Tag,Biotin)KIR2DL3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3) (AA 1-341) protein (GST tag)KIR2DL3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- KIR2DL3 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3))
- 别名
- KIR2DL3 (KIR2DL3 产品)
- 别名
- CD158B2 Protein, CD158b Protein, GL183 Protein, KIR-023GB Protein, KIR-K7b Protein, KIR-K7c Protein, KIRCL23 Protein, NKAT Protein, NKAT2 Protein, NKAT2A Protein, NKAT2B Protein, p58 Protein, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3 Protein, KIR2DL3 Protein
- 背景
- Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules, thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq, Jul 2008]
- 分子量
- predicted molecular mass of 25.4 kDa after removal of the signal peptide. The apparent molecular mass of KIR2DL3-His is 35-55 kDa due to glycosylation.
- UniProt
- P43628
- 途径
- Cancer Immune Checkpoints
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