IFNA2 Protein (AA 24-188) (Fc Tag)
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- 抗原 See all IFNA2 蛋白
- IFNA2 (Interferon, alpha 2 (IFNA2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 24-188
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宿主
- 人
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资源
- Mammalian Cells
- 标记
- This IFNA2 protein is labelled with Fc Tag.
- 原理
- Recombinant human IFNA2 Protein with C-terminal human Fc tag
- 特异性
- IFNA2 (Cys24-Glu188) hFc (Glu99-Ala330)
- 产品特性
- Extracellular Domain Protein
- 纯化方法
- Purified from cell culture supernatant by affinity chromatography
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product IFNA2 蛋白
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Interferon, alpha 2 (IFNA2) (Active) protein
IFNA2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Interferon, alpha 2 (IFNA2) proteinIFNA2 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE
Interferon, alpha 2 (IFNA2) (AA 24-133) protein (GST tag)IFNA2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interferon, alpha 2 (IFNA2) (AA 1-188) protein (GST tag)IFNA2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- IFNA2 (Interferon, alpha 2 (IFNA2))
- 别名
- IFNA2 (IFNA2 产品)
- 别名
- IFN-alphaA Protein, IFNA Protein, IFNA2B Protein, INFA2 Protein, Ifa2 Protein, IFNA2 Protein, interferon alpha 2 Protein, interferon, alpha 2 Protein, interferon-alpha-2 Protein, interferon alpha-2 Protein, IFNA2 Protein, Ifna2 Protein, ifna2 Protein, IFN-ALPHA2 Protein, LOC102142148 Protein
- 背景
- This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded cytokine is a member of the type I interferon family that is produced in response to viral infection as a key part of the innate immune response with potent antiviral, antiproliferative and immunomodulatory properties. This cytokine, like other type I interferons, binds a plasma membrane receptor made of IFNAR1 and IFNAR2 that is ubiquitously expressed, and thus is able to act on virtually all body cells. The encoded protein is effective in reducing the symptoms and duration of the common cold and in treating many types of cancer, including some hematological malignancies and solid tumors. A deficiency of type I interferon in the blood is thought to be a hallmark of severe COVID-19 and may provide a rationale for a combined therapeutic approach. [provided by RefSeq, Aug 2020]
- 分子量
- predicted molecular mass of 45.4 kDa after removal of the signal peptide. The apparent molecular mass of IFNA2-hFc is 55-70 kDa due to glycosylation.
- UniProt
- P01563
- 途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Hepatitis C
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