Integrin beta 4 Protein (ITGB4)
-
- 抗原 See all Integrin beta 4 (ITGB4) 蛋白
- Integrin beta 4 (ITGB4)
- 蛋白类型
- Synthetic Nanodisc
-
宿主
- 人
-
资源
- Mammalian Cells
- 原理
- Human GP150 full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product ITGB4 蛋白
-
Integrin beta 4 (ITGB4) (AA 29-256) protein (His-IF2DI Tag)
ITGB4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Integrin beta 4 (ITGB4) (AA 28-137) protein (GST tag)ITGB4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Integrin beta 4 (ITGB4) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)ITGB4 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
- 说明
-
Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
-
- 抗原
- Integrin beta 4 (ITGB4)
- 别名
- GP150 (ITGB4 产品)
- 别名
- AA407042 Protein, C230078O20 Protein, CD104 Protein, integrin subunit beta 4 Protein, integrin beta 4 Protein, ITGB4 Protein, Itgb4 Protein
- 背景
- This gene encodes an orphan member of the class A rhodopsin-like family of G-protein-coupled receptors (GPCRs). Within the rhodopsin-like family, this gene is a member of the vasopressin-like subfamily that also includes vasopressin and oxytocin receptors. The silencing of this gene, due to promoter methylation, is associated with ovarian cancer progression. All GPCRs have a transmembrane domain that includes seven transmembrane alpha-helices. A general feature of GPCR signaling is the agonist-induced conformational change in the receptor, leading to activation of the heterotrimeric G protein. The activated G protein then binds to and activates numerous downstream effector proteins, which generate second messengers that mediate a broad range of cellular and physiological processes. [provided by RefSeq, Jul 2017]
- 分子量
- The human full length GP150 protein has a MW of 46.4kDa
- UniProt
- Q8NGU9
- 途径
- Integrin Complex
-
