IGF1R
宿主: 人
宿主: 大肠杆菌(E. Coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
限制
仅限研究用
状态
Lyophilized
缓冲液
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
储存条件
-20 °C,-80 °C
储存方法
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Enables insulin-like growth factor binding activity. Involved in several processes, including adrenal gland development, positive regulation of cold-induced thermogenesis, and positive regulation of meiotic cell cycle. Acts upstream of or within several processes, including gland development, peptidyl-tyrosine autophosphorylation, and regulation of intracellular signal transduction. Located in T-tubule. Is integral component of membrane. Is expressed in several structures, including alimentary system, brain, genitourinary system, limb, and lung. Human ortholog(s) of this gene implicated in several diseases, including dementia (multiple), kidney cancer (multiple), liver disease (multiple), nervous system cancer (multiple), and neurodegenerative disease (multiple). Orthologous to human IGF1R (insulin like growth factor 1 receptor). [provided by Alliance of Genome Resources, Apr 2022]
分子量
predicted molecular mass of 104.5 kDa after removal of the signal peptide.