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IGF1 Protein (Fc Tag)

IGF1 宿主: 小鼠 宿主: Mammalian Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN7538330
发货至: 中国
  • 抗原 See all IGF1 蛋白
    IGF1 (Insulin-Like Growth Factor 1 (IGF1))
    蛋白类型
    Recombinant
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    小鼠
    资源
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    Mammalian Cells
    标记
    This IGF1 protein is labelled with Fc Tag.
    原理
    Recombinant mouse IGF1 protein with N-terminal human Fc tag
    特异性
    HFc (Glu99-Ala330) Mouse IGF1 (Gly49-Ala118)
    产品特性
    Extracellular Domain Protein
    纯化方法
    Purified from cell culture supernatant by affinity chromatography
    纯度
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product IGF1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    IGF1 (Insulin-Like Growth Factor 1 (IGF1))
    别名
    IGF1 (IGF1 产品)
    别名
    IGF-I Protein, IGF1A Protein, IGFI Protein, C730016P09Rik Protein, Igf-1 Protein, Igf-I Protein, Npt2B Protein, IGF-1 Protein, IGFIA Protein, IGF-IB Protein, igf1 Protein, IGF-1L Protein, IGF-1a Protein, IGF1 Protein, igf-1 Protein, igf1-A Protein, igf1.S Protein, xigf1 Protein, insulin like growth factor 1 Protein, insulin-like growth factor 1 Protein, insulin-like growth factor I Protein, insulin like growth factor 1 L homeolog Protein, IGF1 Protein, Igf1 Protein, LOC100136741 Protein, igf1 Protein, LOC678666 Protein, igf1.L Protein, LOC104911603 Protein
    背景
    This gene encodes a member of the insulin-like growth factor (IGF) family of proteins that promote growth and development during fetal and postnatal life. This gene is predominantly expressed in the liver and the encoded protein undergoes proteolytic processing to generate a disulfide-linked mature polypeptide. Transgenic disruption of this gene in mice results in reduced postnatal survival and severe growth retardation. Mice lacking the encoded protein exhibit generalized organ hypoplasia including underdevelopment of the central nervous system and developmental defects in bone, muscle and reproductive systems. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Sep 2015]
    分子量
    predicted molecular mass of 33.8 kDa after removal of the signal peptide. The apparent molecular mass of hFc-mIGF1 is 35-55 kDa due to glycosylation.
    UniProt
    P05017
    途径
    RTK signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Hormone Activity, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Activated T Cell Proliferation, Positive Regulation of fat Cell Differentiation
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