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ILDR2 蛋白

ILDR2 宿主: 人 宿主: Mammalian Cells Synthetic Nanodisc
产品编号 ABIN7538328
发货至: 中国
  • 抗原 See all ILDR2 products
    ILDR2 (Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2))
    蛋白类型
    Synthetic Nanodisc
    宿主
    资源
    • 2
    • 1
    • 1
    • 1
    Mammalian Cells
    原理
    Human ILDR2 full length protein-synthetic nanodisc
    产品特性
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
  • 说明

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    ILDR2 (Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2))
    别名
    ILDR2 (ILDR2 产品)
    别名
    C1orf32 Protein, RP4-782G3.2 Protein, dJ782G3.1 Protein, immunoglobulin like domain containing receptor 2 Protein, ILDR2 Protein
    背景
    May be involved in ER stress pathways with effects on lipid homeostasis and insulin secretion. With ILDR1 and LSR, involved in the maintain of the epithelial barrier function through the recruitment of MARVELD2/tricellulin to tricellular tight junctions. Also functions as a B7-like protein family member expressed on immune cells and inflamed tissue and with T-cell inhibitory activity.
    分子量
    The human full length ILDR2 protein has a MW of 71.2 kDa
    UniProt
    Q71H61
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