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GABBR2 蛋白

GABBR2 宿主: 人 宿主: Mammalian Cells Synthetic Nanodisc
产品编号 ABIN7538298
发货至: 中国
  • 抗原 See all GABBR2 蛋白
    GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))
    蛋白类型
    Synthetic Nanodisc
    宿主
    • 3
    • 1
    资源
    • 2
    • 1
    Mammalian Cells
    原理
    Human GABR2 full length protein-synthetic nanodisc
    产品特性
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
    Top Product
    Discover our top product GABBR2 蛋白
  • 说明

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))
    别名
    GABR2 (GABBR2 产品)
    别名
    Gpr51 Protein, GABABR2 Protein, GPR51 Protein, GPRC3B Protein, HG20 Protein, HRIHFB2099 Protein, Gb2 Protein, Gm425 Protein, GABA(B)R2 Protein, si:dkey-190l1.2 Protein, gamma-aminobutyric acid type B receptor subunit 2 Protein, gamma-aminobutyric acid (GABA) B receptor, 2 Protein, gamma-aminobutyric acid (GABA) B receptor, 2 S homeolog Protein, GABBR2 Protein, LOC100448699 Protein, gabbr2 Protein, Gabbr2 Protein, gabbr2.S Protein
    背景
    The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010]
    分子量
    The human full length GABR2 protein has a MW of 105.8kDa
    UniProt
    O75899
    途径
    cAMP Metabolic Process
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