GABBR2 蛋白
GABBR2
宿主: 人
宿主: Mammalian Cells
Synthetic Nanodisc
-
- 抗原 See all GABBR2 蛋白
- GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))
- 蛋白类型
- Synthetic Nanodisc
-
宿主
- 人
-
资源
- Mammalian Cells
- 原理
- Human GABR2 full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product GABBR2 蛋白
-
gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 1-883) protein (GST tag)
GABBR2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
-
- 说明
-
Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
-
- 抗原
- GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))
- 别名
- GABR2 (GABBR2 产品)
- 别名
- Gpr51 Protein, GABABR2 Protein, GPR51 Protein, GPRC3B Protein, HG20 Protein, HRIHFB2099 Protein, Gb2 Protein, Gm425 Protein, GABA(B)R2 Protein, si:dkey-190l1.2 Protein, gamma-aminobutyric acid type B receptor subunit 2 Protein, gamma-aminobutyric acid (GABA) B receptor, 2 Protein, gamma-aminobutyric acid (GABA) B receptor, 2 S homeolog Protein, GABBR2 Protein, LOC100448699 Protein, gabbr2 Protein, Gabbr2 Protein, gabbr2.S Protein
- 背景
- The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010]
- 分子量
- The human full length GABR2 protein has a MW of 105.8kDa
- UniProt
- O75899
- 途径
- cAMP Metabolic Process
-
You are here:
