Galanin Receptor 1 Protein (GALR1)
GALR1
宿主: 人
宿主: Mammalian Cells
Synthetic Nanodisc
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- 抗原 See all Galanin Receptor 1 (GALR1) products
- Galanin Receptor 1 (GALR1)
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human GALR1 full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- Galanin Receptor 1 (GALR1)
- 别名
- GALR1 (GALR1 产品)
- 别名
- GALNR Protein, GALNR1 Protein, GALR1 Protein, GALR Protein, Galnr1 Protein, galanin receptor 1 Protein, transcription regulator. LacI family, galactose related Protein, LacI family transcriptional regulatory protein Protein, galactose operon repressor Protein, GALR1 Protein, galr1 Protein, galR Protein, galR1 Protein, Galr1 Protein, LOC100037697 Protein
- 背景
- The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart. [provided by RefSeq, Jul 2008]
- 分子量
- The human full length GALR1 protein has a MW of 39kDa
- UniProt
- P47211
- 途径
- cAMP Metabolic Process
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