GPRC6A 蛋白
GPRC6A
宿主: 人
宿主: Mammalian Cells
Synthetic Nanodisc
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- 抗原 See all GPRC6A products
- GPRC6A (G Protein-Coupled Receptor, Family C, Group 6, Member A (GPRC6A))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human GPC6A full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- GPRC6A (G Protein-Coupled Receptor, Family C, Group 6, Member A (GPRC6A))
- 别名
- GPC6A (GPRC6A 产品)
- 别名
- gpcr Protein, GPCR Protein, bA86F4.3 Protein, G protein-coupled receptor class C group 6 member A Protein, G protein-coupled receptor, family C, group 6, member A Protein, G protein-coupled receptor, class C, group 6, member A Protein, GPRC6A Protein, gprc6a Protein, Gprc6a Protein
- 背景
- Members of family C of the G protein-coupled receptor (GPCR) superfamily, such as GPRC6A, are characterized by an evolutionarily conserved amino acid-sensing motif linked to an intramembranous 7-transmembrane loop region. Several members of GPCR family C, including GPRC6A, also have a long N-terminal domain (summary by Pi et al., 2005 [PubMed 16199532]).[supplied by OMIM, Nov 2010]
- 分子量
- The human full length GPC6A protein has a MW of 104.8kDa
- UniProt
- Q5T6X5
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