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GPR68 蛋白

GPR68 宿主: 人 宿主: Mammalian Cells Synthetic Nanodisc
产品编号 ABIN7538286
发货至: 中国
  • 抗原 See all GPR68 products
    GPR68 (G Protein-Coupled Receptor 68 (GPR68))
    蛋白类型
    Synthetic Nanodisc
    宿主
    • 1
    • 1
    资源
    • 2
    Mammalian Cells
    原理
    Human OGR1 full length protein-synthetic nanodisc
    产品特性
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
  • 说明

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    GPR68 (G Protein-Coupled Receptor 68 (GPR68))
    别名
    OGR1 (GPR68 产品)
    别名
    GPR68 Protein, GPR12A Protein, OGR1 Protein, BB131428 Protein, Ogr1 Protein, G protein-coupled receptor 68 Protein, GPR68 Protein, LOC100348269 Protein, Gpr68 Protein
    背景
    The protein encoded by this gene is a G protein-coupled receptor for sphingosylphosphorylcholine. The encoded protein is a proton-sensing receptor, inactive at pH 7.8 but active at pH 6.8. Mutations in this gene are a cause of amelogenesis imperfecta. [provided by RefSeq, Feb 2017]
    分子量
    The human full length OGR1 protein has a MW of 41.1kDa
    UniProt
    Q15743
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