GPR62 蛋白
GPR62
宿主: 人
宿主: Mammalian Cells
Synthetic Nanodisc
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- 抗原 See all GPR62 蛋白
- GPR62 (G Protein-Coupled Receptor 62 (GPR62))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human GPR62 full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product GPR62 蛋白
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G Protein-Coupled Receptor 62 (GPR62) (AA 314-368) protein (GST tag)
GPR62 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- GPR62 (G Protein-Coupled Receptor 62 (GPR62))
- 别名
- GPR62 (GPR62 产品)
- 别名
- GPR62 Protein, GPCR8 Protein, KPG_005 Protein, 4933402E03Rik Protein, G protein-coupled receptor 62 Protein, GPR62 Protein, Gpr62 Protein
- 背景
- Orphan G-protein coupled receptor. Constitutively activates the G(q/11)/inositol phosphate and the G(s)-alpha/cAMP signaling pathways (PubMed:28827538). Has spontaneous activity for beta-arrestin recruitment (PubMed:28827538). Shows a reciprocal modulation of signaling functions with the melatonin receptor MTNR1B most likely through receptor heteromerization (PubMed:28827538).[UniProtKB/Swiss-Prot Function]
- 分子量
- The human full length GPR62 protein has a MW of 37.6kDa
- UniProt
- Q9BZJ7
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