GPR31 蛋白
GPR31
宿主: 人
宿主: Mammalian Cells
Synthetic Nanodisc
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- 抗原 See all GPR31 蛋白
- GPR31 (G Protein-Coupled Receptor 31 (GPR31))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human GPR31 full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product GPR31 蛋白
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G Protein-Coupled Receptor 31 (GPR31) (AA 1-319) protein (GST tag)
GPR31 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- GPR31 (G Protein-Coupled Receptor 31 (GPR31))
- 别名
- GPR31 (GPR31 产品)
- 别名
- 12-HETER Protein, HETER Protein, HETER1 Protein, GPR31 Protein, GPR31c(t) Protein, Gpr31 Protein, Gpr31c Protein, G protein-coupled receptor 31 Protein, G protein-coupled receptor 31, D17Leh66b region Protein, GPR31 Protein, Gpr31 Protein, Gpr31b Protein
- 背景
- High-affinity receptor for 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid (12-S-HETE). 12-(S)-HETE is an arachidonic acid metabolite secreted by platelets and tumor cells, and known to induce endothelial cells retraction allowing invasive cell access to the subendothelial matrix, which is a critical step for extravasation or metastasis. Ligand-binding lead to activation of ERK1/2 (MAPK3/MAPK1), MEK, and NF-kappa-B.[UniProtKB/Swiss-Prot Function]
- 分子量
- The human full length GPR31 protein has a MW of 35.1kDa
- UniProt
- O00270
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