GPR161 蛋白
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- 抗原 See all GPR161 蛋白
- GPR161 (G Protein-Coupled Receptor 161 (GPR161))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human GP161 full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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- Discover our top product GPR161 蛋白
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G Protein-Coupled Receptor 161 (GPR161) (AA 362-460) protein (GST tag)
GPR161 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
G Protein-Coupled Receptor 161 (GPR161) (AA 1-28), (partial) protein (GST tag)GPR161 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 90 % ELISA
G Protein-Coupled Receptor 161 (GPR161) (AA 1-28), (Extracellular), (partial) protein (GST tag)GPR161 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- GPR161 (G Protein-Coupled Receptor 161 (GPR161))
- 别名
- GP161 (GPR161 产品)
- 别名
- RE2 Protein, Gm208 Protein, Gm208Gpr Protein, vl Protein, RGD1563245 Protein, si:bz20i5.4 Protein, si:rp71-20i5.4 Protein, G protein-coupled receptor 161 Protein, GPR161 Protein, Gpr161 Protein, gpr161 Protein
- 背景
- The protein encoded by this gene is an orphan G protein-coupled receptor whose ligand is unknown. This gene is overexpressed in triple-negative breast cancer, and disruption of this gene slows the proliferation of basal breast cancer cells. Therefore, this gene is a potential drug target for triple-negative breast cancer. [provided by RefSeq, Mar 2017]
- 分子量
- The human full length GP161 protein has a MW of 58.6kDa
- UniProt
- Q8N6U8
- 途径
- cAMP Metabolic Process
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