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G Protein-Coupled Receptor 12 Protein (GPR12)

GPR12 宿主: 人 宿主: Mammalian Cells Synthetic Nanodisc
产品编号 ABIN7538253
发货至: 中国
  • 抗原 See all G Protein-Coupled Receptor 12 (GPR12) 蛋白
    G Protein-Coupled Receptor 12 (GPR12)
    蛋白类型
    Synthetic Nanodisc
    宿主
    • 3
    • 1
    资源
    • 2
    • 2
    Mammalian Cells
    原理
    Human GPR12 full length protein-synthetic nanodisc
    产品特性
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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    Discover our top product GPR12 蛋白
  • 说明

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    G Protein-Coupled Receptor 12 (GPR12)
    别名
    GPR12 (GPR12 产品)
    别名
    GPCR12 Protein, GPCR21 Protein, Gpcr12 Protein, Gpcr01 Protein, Gpcr20 Protein, Gpcr21 Protein, G protein-coupled receptor 12 Protein, G-protein coupled receptor 12 Protein, GPR12 Protein, Gpr12 Protein
    背景
    Promotes neurite outgrowth and blocks myelin inhibition in neurons (By similarity). Receptor with constitutive G(s) signaling activity that stimulates cyclic AMP production.[UniProtKB/Swiss-Prot Function]
    分子量
    The human full length GPR12 protein has a MW of 36.7kDa
    UniProt
    P47775
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