FZD8 蛋白
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- 抗原 See all FZD8 蛋白
- FZD8 (Frizzled Family Receptor 8 (FZD8))
- 蛋白类型
- Synthetic Nanodisc
- 宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human FZD8 full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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- Discover our top product FZD8 蛋白
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Frizzled Family Receptor 8 (FZD8) (AA 72-161) protein (GST tag)
FZD8 宿主: 人 宿主: 小麦胚 Recombinant AA, AP, ELISA, WB
Frizzled Family Receptor 8 (FZD8) protein (His tag)FZD8 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
Frizzled Family Receptor 8 (FZD8) protein (Biotin,His-Avi Tag)FZD8 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- FZD8 (Frizzled Family Receptor 8 (FZD8))
- 别名
- FZD8 (FZD8 产品)
- 别名
- FZ-8 Protein, hFZ8 Protein, FZD8 Protein, Fz-8 Protein, frizzled8 Protein, xfz8 Protein, Xfz8 Protein, frizzled-8 Protein, hfz8 Protein, Fz8 Protein, fzd8 Protein, fz5 Protein, fz8a Protein, fzc Protein, wu:fd02c05 Protein, zg05 Protein, ZG06 Protein, Zfz8b Protein, fz6 Protein, fz8b Protein, fzA Protein, ik:tdsubc_1e1 Protein, xx:tdsubc_1e1 Protein, zfzA Protein, frizzled class receptor 8 Protein, frizzled class receptor 8 S homeolog Protein, frizzled class receptor 8 L homeolog Protein, frizzled class receptor 8a Protein, frizzled class receptor 8b Protein, FZD8 Protein, fzd8.S Protein, fzd8 Protein, Fzd8 Protein, fzd8.L Protein, fzd8a Protein, fzd8b Protein
- 背景
- This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq, Jul 2008]
- 分子量
- The human full length FZD8 protein has a MW of 73.3kDa
- UniProt
- Q9H461
- 途径
- WNT signaling
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