FZD3 蛋白
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- 抗原 See all FZD3 蛋白
- FZD3 (Frizzled Family Receptor 3 (FZD3))
- 蛋白类型
- Synthetic Nanodisc
- 宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human FZD3 full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product FZD3 蛋白
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- FZD3 (Frizzled Family Receptor 3 (FZD3))
- 别名
- FZD3 (FZD3 产品)
- 别名
- Fz-3 Protein, FZ-3 Protein, fz3 Protein, Xfz3 Protein, frz3 Protein, hfz3 Protein, frz-3 Protein, frizzled3 Protein, frizzled-3 Protein, FZD3 Protein, AU020229 Protein, D930050A07Rik Protein, Fz3 Protein, fz9 Protein, fzd3 Protein, zg09 Protein, fzd3l Protein, frizzled class receptor 3 Protein, frizzled class receptor 3 L homeolog Protein, frizzled class receptor 3a Protein, frizzled class receptor 3b Protein, FZD3 Protein, fzd3 Protein, fzd3.L Protein, Fzd3 Protein, fzd3a Protein, fzd3b Protein
- 背景
- This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development. Alternative splicing results in multiple transcript variants. This gene is a susceptibility locus for schizophrenia. [provided by RefSeq, Dec 2010]
- 分子量
- The human full length FZD3 protein has a MW of 76.3kDa
- UniProt
- Q9NPG1
- 途径
- WNT signaling, Tube Formation
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