FZD2 蛋白
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- 抗原 See all FZD2 蛋白
- FZD2 (Frizzled Family Receptor 2 (FZD2))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human FZD2 full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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- Discover our top product FZD2 蛋白
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Frizzled Family Receptor 2 (FZD2) protein (Fc Tag)
FZD2 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Frizzled Family Receptor 2 (FZD2) (AA 192-245) protein (GST tag)FZD2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Frizzled Family Receptor 2 (FZD2) (AA 24-156) protein (Fc Tag)FZD2 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Frizzled Family Receptor 2 (FZD2) (AA 24-190) protein (Fc Tag)FZD2 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- FZD2 (Frizzled Family Receptor 2 (FZD2))
- 别名
- FZD2 (FZD2 产品)
- 别名
- BG01711 Protein, CG9739 Protein, D-Fz2 Protein, D-fz2 Protein, DFZ2 Protein, DFz-2 Protein, DFz2 Protein, Dfrz2 Protein, Dfz2 Protein, Dfz[[2]] Protein, Dm Fz2 Protein, Dmel\\CG9739 Protein, FZ2 Protein, Fz2 Protein, dFz2 Protein, dfz(2) Protein, dfz2 Protein, dfz2r Protein, frz2 Protein, fz-2 Protein, fz8 Protein, zfz2 Protein, zg08 Protein, cb383 Protein, wu:fb70g09 Protein, FZD2 Protein, fzE2 Protein, hFz2 Protein, Fz-10 Protein, Fzd10 Protein, cFz-2 Protein, frizzled2 Protein, fz2 Protein, xfz2 Protein, AL033370 Protein, AW456835 Protein, Fz10 Protein, Mfz10 Protein, Mfz10a Protein, frizzled 2 Protein, frizzled class receptor 2 Protein, frizzled class receptor 2 S homeolog Protein, fz2 Protein, fzd2 Protein, FZD2 Protein, Fzd2 Protein, fzd2.S Protein
- 背景
- This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. This gene encodes a protein that is coupled to the beta-catenin canonical signaling pathway. Competition between the wingless-type MMTV integration site family, member 3A and wingless-type MMTV integration site family, member 5A gene products for binding of this protein is thought to regulate the beta-catenin-dependent and -independent pathways. [provided by RefSeq, Dec 2010]
- 分子量
- The human full length FZD2 protein has a MW of 63.6kDa
- UniProt
- Q14332
- 途径
- WNT signaling
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