FPR2 蛋白
FPR2
宿主: 人
宿主: Mammalian Cells
Synthetic Nanodisc
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- 抗原 See all FPR2 蛋白
- FPR2 (Formyl Peptide Receptor 2 (FPR2))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human FPR2 full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product FPR2 蛋白
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Formyl Peptide Receptor 2 (FPR2) (AA 163-205) protein (GST tag)
FPR2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- FPR2 (Formyl Peptide Receptor 2 (FPR2))
- 别名
- FPR2 (FPR2 产品)
- 别名
- ALXR Protein, FMLP-R-II Protein, FMLPX Protein, FPR2A Protein, FPRH1 Protein, FPRH2 Protein, FPRL1 Protein, HM63 Protein, LXA4R Protein, E330010I07Rik Protein, Fpr-rs2 Protein, Fprl1 Protein, ALX Protein, Fpr-rs1 Protein, Fpr-s1 Protein, LXA4-R Protein, Lxa4r Protein, FMLP-R-I Protein, FPR2 Protein, formyl peptide receptor 2 Protein, formyl peptide receptor 3 Protein, N-formyl peptide receptor 2 Protein, FPR2 Protein, Fpr2 Protein, Fpr3 Protein, LOC100444626 Protein
- 背景
- Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophil chemotactic factors (PubMed:1374236). Binding of FMLP to the receptor causes activation of neutrophils (PubMed:1374236). This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system (PubMed:1374236). The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4) (PubMed:9547339). Receptor for the chemokine-like protein FAM19A5, mediating FAM19A5-stimulated macrophage chemotaxis and the inhibitory effect on TNFSF11/RANKL-induced osteoclast differentiation (By similarity).[UniProtKB/Swiss-Prot Function]
- 分子量
- The human full length FPR2 protein has a MW of 39kDa
- UniProt
- P25090
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