EDNRB 蛋白
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- 抗原 See all EDNRB 蛋白
- EDNRB (Endothelin Receptor Type B (EDNRB))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human EDNRB full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product EDNRB 蛋白
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Endothelin Receptor Type B (EDNRB) (AA 27-101) protein (GST tag)
EDNRB 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Endothelin Receptor Type B (EDNRB) (AA 1-442) protein (GST tag)EDNRB 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Endothelin Receptor Type B (EDNRB) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)EDNRB 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- EDNRB (Endothelin Receptor Type B (EDNRB))
- 别名
- EDNRB (EDNRB 产品)
- 别名
- ABCDS Protein, ET-B Protein, ET-BR Protein, ETB Protein, ETBR Protein, ETRB Protein, HSCR Protein, HSCR2 Protein, WS4A Protein, Ednra Protein, Etb Protein, ETR-b Protein, ETb Protein, Sox10m1 Protein, EDNRB Protein, abcds Protein, etb Protein, etrb Protein, hscr Protein, hscr2 Protein, endothelin receptor type B Protein, EDNRB Protein, Ednrb Protein, ednrb Protein
- 背景
- The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016]
- 分子量
- The human full length EDNRB protein has a MW of 49.6kDa
- UniProt
- P24530
- 途径
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process
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