Endothelin-1 Receptor 蛋白
-
- 抗原 See all Endothelin-1 Receptor (EDNRA) 蛋白
- Endothelin-1 Receptor (EDNRA) (Endothelin Receptor Type A (EDNRA))
- 蛋白类型
- Synthetic Nanodisc
-
宿主
- 人
-
资源
- Mammalian Cells
- 原理
- Human EDNRA full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product EDNRA 蛋白
-
Endothelin Receptor Type A (EDNRA) (AA 1-427) protein (GST tag)
EDNRA 宿主: 人 宿主: 小麦胚 Recombinant WB, AP, AA, ELISA
Endothelin Receptor Type A (EDNRA) (AA 18-80) protein (GST tag)EDNRA 宿主: 人 宿主: 小麦胚 Recombinant WB, AP, AA, ELISA
Endothelin Receptor Type A (EDNRA) (AA 39-280) protein (His tag)EDNRA 宿主: Staphylococcus aureus 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
-
- 说明
-
Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
-
- 抗原
- Endothelin-1 Receptor (EDNRA) (Endothelin Receptor Type A (EDNRA))
- 别名
- EDNRA (EDNRA 产品)
- 别名
- ET-A Protein, ETA Protein, ETA-R Protein, ETAR Protein, ETRA Protein, hET-AR Protein, ET-AR Protein, Endor Protein, Eta Protein, RGD1559432 Protein, ETa Protein, Gpcr10 Protein, ednr-a Protein, ednra Protein, wu:fb75g12 Protein, ednraa Protein, eta Protein, etar Protein, etra Protein, zgc:85942 Protein, endothelin receptor type A Protein, endothelin receptor type Aa Protein, endothelin receptor type A L homeolog Protein, endothelin receptor type Ab Protein, EDNRA Protein, Ednra Protein, ednraa Protein, ednra.L Protein, ednra Protein, ednrab Protein
- 背景
- This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
- 分子量
- The human full length EDNRA protein has a MW of 48.7kDa
- UniProt
- P25101
- 途径
- cAMP Metabolic Process
-
