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EGFRviii Protein (AA 25-645) (His tag)

EGFRv3 宿主: 人 宿主: Mammalian Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN7538221
发货至: 中国
  • 抗原 See all EGFRviii (EGFRv3) products
    EGFRviii (EGFRv3) (EGFR vIII (EGFRv3))
    蛋白类型
    Recombinant
    产品特性
    AA 25-645
    宿主
    资源
    • 9
    Mammalian Cells
    标记
    This EGFRviii protein is labelled with His tag.
    原理
    Recombinant Human EGFRVIII Protein with C-terminal 6xHis tag
    特异性
    EGFRVIII (Leu25-Ser645 267aa) 6xHis tag
    产品特性
    Extracellular Domain Protein
    纯化方法
    Purified from cell culture supernatant by affinity chromatography
    纯度
    The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    EGFRviii (EGFRv3) (EGFR vIII (EGFRv3))
    别名
    EGFRVIII (EGFRv3 产品)
    背景
    The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.
    分子量
    predicted molecular mass of 39.5 kDa after removal of the signal peptide. The apparent molecular mass of EGFRVIII-His is 55-100 kDa due to glycosylation.
    UniProt
    P00533
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