DARC 蛋白
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- 抗原 See all DARC 蛋白
- DARC (Duffy Blood Group, Chemokine Receptor (DARC))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human ACKR1 full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product DARC 蛋白
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Duffy Blood Group, Chemokine Receptor (DARC) (AA 1-336) protein (GST tag)
DARC 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Duffy Blood Group, Chemokine Receptor (DARC) proteinDARC 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % WB, SDS, ELISA, IP
Duffy Blood Group, Chemokine Receptor (DARC) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)DARC 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- DARC (Duffy Blood Group, Chemokine Receptor (DARC))
- 别名
- ACKR1 (DARC 产品)
- 别名
- DARC Protein, FY Protein, ACKR1 Protein, CCBP1 Protein, CD234 Protein, Dfy Protein, GPD Protein, GpFy Protein, WBCQ1 Protein, AA162249 Protein, Ackr1 Protein, ESTM35 Protein, Duffy blood group, chemokine receptor Protein, atypical chemokine receptor 1 (Duffy blood group) Protein, atypical chemokine receptor 1 Protein, DARC Protein, ACKR1 Protein, Ackr1 Protein
- 背景
- The protein encoded by this gene is a glycosylated membrane protein and a non-specific receptor for several chemokines. The encoded protein is the receptor for the human malarial parasites Plasmodium vivax and Plasmodium knowlesi. Polymorphisms in this gene are the basis of the Duffy blood group system. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- 分子量
- The human full length ACKR1 protein has a MW of 35.6kDa
- UniProt
- Q16570
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