DRD4 蛋白
DRD4
宿主: 人
宿主: Mammalian Cells
Synthetic Nanodisc
-
- 抗原 See all DRD4 蛋白
- DRD4 (Dopamine Receptor D4 (DRD4))
- 蛋白类型
- Synthetic Nanodisc
-
宿主
- 人
-
资源
- Mammalian Cells
- 原理
- Human DRD4 full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product DRD4 蛋白
-
-
- 说明
-
Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
-
- 抗原
- DRD4 (Dopamine Receptor D4 (DRD4))
- 别名
- DRD4 (DRD4 产品)
- 别名
- Drd4b Protein, si:ch211-69h5.1 Protein, zgc:123021 Protein, D4DR Protein, AW125663 Protein, D4R Protein, Drd-4 Protein, D4RA Protein, DRD4 Protein, Drd4c Protein, dopamine receptor D4 related sequence Protein, dopamine receptor D4 Protein, dopamine receptor D4b Protein, drd4-rs Protein, DRD4 Protein, Drd4 Protein, SRU_2808 Protein, MSMEG_3522 Protein, drd4b Protein
- 背景
- This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats, the sequence shown contains four repeats. [provided by RefSeq, Jul 2008]
- 分子量
- The human full length DRD4 protein has a MW of 43.9kDa
- UniProt
- P21917
- 途径
- cAMP Metabolic Process, Synaptic Membrane, Proton Transport, Photoperiodism, Negative Regulation of Transporter Activity
-
You are here:
