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CRLF2 Protein (AA 23-231) (His tag)

CRLF2 宿主: 人 宿主: Mammalian Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN7538213
发货至: 中国
  • 抗原 See all CRLF2 蛋白
    CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
    蛋白类型
    Recombinant
    产品特性
    AA 23-231
    宿主
    • 10
    • 8
    • 1
    • 1
    资源
    • 6
    • 5
    • 5
    • 2
    • 1
    • 1
    Mammalian Cells
    标记
    This CRLF2 protein is labelled with His tag.
    原理
    Recombinant Human CRLF2 Protein with C-terminal 6XHis tag
    特异性
    CRLF2 (Gln23-Lys231) 6xHis tag
    产品特性
    Extracellular Domain Protein
    纯化方法
    Purified from cell culture supernatant by affinity chromatography
    纯度
    The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product CRLF2 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
    别名
    CRLF2 (CRLF2 产品)
    别名
    CRLF2 Protein, CRL2 Protein, CRLF2Y Protein, TSLPR Protein, CRLM2 Protein, Ly114 Protein, Tpte2 Protein, Tslpr Protein, Crl2 Protein, cytokine receptor like factor 2 Protein, cytokine receptor-like factor 2 Protein, CRLF2 Protein, Crlf2 Protein
    背景
    This gene encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14, or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014]
    分子量
    predicted molecular mass of 25.0 kDa after removal of the signal peptide. The apparent molecular mass of CRLF2-His is 25-55 kDa due to glycosylation.
    UniProt
    Q9HC73
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