CRHR2 蛋白
CRHR2
宿主: 人
宿主: Mammalian Cells
Synthetic Nanodisc
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- 抗原 See all CRHR2 蛋白
- CRHR2 (Corticotropin Releasing Hormone Receptor 2 (CRHR2))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human CRFR2 full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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- Discover our top product CRHR2 蛋白
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Corticotropin Releasing Hormone Receptor 2 (CRHR2) (AA 1-411) protein (GST tag)
CRHR2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- CRHR2 (Corticotropin Releasing Hormone Receptor 2 (CRHR2))
- 别名
- CRFR2 (CRHR2 产品)
- 别名
- CRF-RB Protein, CRF2 Protein, CRFR2 Protein, HM-CRF Protein, CRF-R2 Protein, CRFR2alpha Protein, CRFR2beta Protein, Crfr2 Protein, Crf2r Protein, CRH-R2 Protein, crhr2-A Protein, corticotropin releasing hormone receptor 2 Protein, corticotropin releasing hormone receptor 2 S homeolog Protein, CRHR2 Protein, Crhr2 Protein, crhr2.S Protein
- 背景
- The protein encoded by this gene belongs to the G-protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH-related peptides such as urocortin. CRH is synthesized in the hypothalamus, and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. Studies in mice suggest that this receptor maybe involved in mediating cardiovascular homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jan 2011]
- 分子量
- The human full length CRFR2 protein has a MW of 47.7kDa
- UniProt
- Q13324
- 途径
- Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Feeding Behaviour
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