Complement Factor I Protein (CFI) (AA 19-583) (His tag)
CFI
宿主: 人
宿主: Mammalian Cells
Recombinant
The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
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- 抗原 See all Complement Factor I (CFI) 蛋白
- Complement Factor I (CFI)
- 蛋白类型
- Recombinant
- 产品特性
- AA 19-583
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宿主
- 人
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资源
- Mammalian Cells
- 标记
- This Complement Factor I protein is labelled with His tag.
- 原理
- Recombinant human CFI Protein with C-terminal 6xHis tag
- 特异性
- CFI (Lys19-Val583) 6xHis tag
- 产品特性
- Extracellular Domain Protein
- 纯化方法
- Purified from cell culture supernatant by affinity chromatography
- 纯度
- The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
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- Discover our top product CFI 蛋白
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Complement Factor I (CFI) (AA 19-583) protein (His tag)
CFI 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Complement Factor I (CFI) (AA 19-118) protein (GST tag)CFI 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- Complement Factor I (CFI)
- 别名
- CFI (CFI 产品)
- 别名
- cfi Protein, MGC53615 Protein, Cfi Protein, factor I Protein, IF Protein, gb:ai721528 Protein, ahus3 Protein, c3b-ina Protein, c3bc4bi Protein, c3bina Protein, kaf Protein, CFI Protein, AHUS3 Protein, C3BINA Protein, C3b-INA Protein, FI Protein, KAF Protein, complement factor I S homeolog Protein, complement factor I L homeolog Protein, complement factor I Protein, complement component factor i Protein, cfi.S Protein, cfi.L Protein, CFI Protein, cfi Protein, Cfi Protein
- 背景
- This gene encodes a serine proteinase that is essential for regulating the complement cascade. The encoded preproprotein is cleaved to produce both heavy and light chains, which are linked by disulfide bonds to form a heterodimeric glycoprotein. This heterodimer can cleave and inactivate the complement components C4b and C3b, and it prevents the assembly of the C3 and C5 convertase enzymes. Defects in this gene cause complement factor I deficiency, an autosomal recessive disease associated with a susceptibility to pyogenic infections. Mutations in this gene have been associated with a predisposition to atypical hemolytic uremic syndrome, a disease characterized by acute renal failure, microangiopathic hemolytic anemia and thrombocytopenia. Primary glomerulonephritis with immune deposits and age-related macular degeneration are other conditions associated with mutations of this gene. [provided by RefSeq, Dec 2015]
- 分子量
- predicted molecular mass of 64.3 kDa after removal of the signal peptide. The apparent molecular mass of CFI-His is 70-100 kDa due to glycosylation.
- UniProt
- P05156
- 途径
- Complement System
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