F2RL2 蛋白
F2RL2
宿主: 人
宿主: Mammalian Cells
Synthetic Nanodisc
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- 抗原 See all F2RL2 蛋白
- F2RL2 (Coagulation Factor II (thrombin) Receptor-Like 2 (F2RL2))
- 蛋白类型
- Synthetic Nanodisc
- 宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human PAR3 full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product F2RL2 蛋白
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- F2RL2 (Coagulation Factor II (thrombin) Receptor-Like 2 (F2RL2))
- 别名
- PAR3 (F2RL2 产品)
- 别名
- PAR-3 Protein, PAR3 Protein, par3 Protein, Cf-2 Protein, Cf2 Protein, FII Protein, thrombin Protein, F730031A08 Protein, f2 Protein, f2rl2 Protein, coagulation factor II thrombin receptor like 2 Protein, coagulation factor II (thrombin) receptor-like 2 Protein, coagulation factor II Protein, coagulation factor II, thrombin Protein, coagulation factor II, thrombin L homeolog Protein, coagulation factor II (thrombin) receptor-like 2 L homeolog Protein, F2RL2 Protein, f2rl2 Protein, F2 Protein, F2rl2 Protein, f2.L Protein, f2rl2.L Protein
- 背景
- This gene encodes a member of the protease-activated receptor (PAR) family which is a subfamily of the seven transmembrane G protein-coupled cell surface receptor family. The encoded protein acts as a cofactor in the thrombin-mediated cleavage and activation of the protease-activated receptor family member PAR4. The encoded protein plays an essential role in hemostasis and thrombosis. Alternate splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Feb 2012]
- 分子量
- The human full length PAR3 protein has a MW of 42.5kDa
- UniProt
- O00254
- 途径
- Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling
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