PAR1 蛋白
F2R
宿主: 人
宿主: Mammalian Cells
Synthetic Nanodisc
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- 抗原 See all PAR1 (F2R) 蛋白
- PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human PAR1 full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product F2R 蛋白
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Coagulation Factor II (thrombin) Receptor (F2R) (AA 42-102) protein (GST tag)
F2R 宿主: 人 宿主: 小麦胚 Recombinant WB, AP, AA, ELISA
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))
- 别名
- PAR1 (F2R 产品)
- 别名
- CF2R Protein, HTR Protein, PAR-1 Protein, PAR1 Protein, TR Protein, Par1 Protein, TRGPC Protein, AI482343 Protein, Cf2r Protein, ThrR Protein, Par-1 Protein, f2r-a Protein, par1 Protein, coagulation factor II thrombin receptor Protein, coagulation factor II (thrombin) receptor Protein, coagulation factor 2 (thrombin) receptor L homeolog Protein, F2R Protein, F2r Protein, f2r.L Protein
- 背景
- Coagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled receptor family member. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
- 分子量
- The human full length PAR1 protein has a MW of 47.4kDa
- UniProt
- P25116
- 途径
- Nuclear Receptor Transcription Pathway, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus
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