CCKBR 蛋白
CCKBR
宿主: 人
宿主: Mammalian Cells
Synthetic Nanodisc
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- 抗原 See all CCKBR 蛋白
- CCKBR (Cholecystokinin B Receptor (CCKBR))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human GASR full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product CCKBR 蛋白
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Cholecystokinin B Receptor (CCKBR) (AA 215-327) protein (GST tag)
CCKBR 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Cholecystokinin B Receptor (CCKBR) (AA 1-100) protein (GST tag)CCKBR 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- CCKBR (Cholecystokinin B Receptor (CCKBR))
- 别名
- GASR (CCKBR 产品)
- 别名
- CCKBR Protein, LOC100232835 Protein, CCK-B Protein, CCK2R Protein, GASR Protein, Cck2r Protein, Cholrec Protein, CCKR-2 Protein, CCK-BR Protein, CCK2-R Protein, CCK-CHR Protein, cholecystokinin B receptor Protein, cholecystokinin receptor-like Protein, CCKBR Protein, LOC100232835 Protein, Cckbr Protein
- 背景
- This gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. Alternative splicing results in multiple transcript variants. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors. [provided by RefSeq, Dec 2015]
- 分子量
- The human full length GASR protein has a MW of 48.4kDa
- UniProt
- P32239
- 途径
- Positive Regulation of Peptide Hormone Secretion, Feeding Behaviour
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