CCKAR 蛋白
CCKAR
宿主: 人
宿主: Mammalian Cells
Synthetic Nanodisc
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- 抗原 See all CCKAR 蛋白
- CCKAR (Cholecystokinin A Receptor (CCKAR))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human CCKAR full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product CCKAR 蛋白
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- CCKAR (Cholecystokinin A Receptor (CCKAR))
- 别名
- CCKAR (CCKAR 产品)
- 别名
- CCK-XL Protein, cck-a Protein, cck1-r Protein, cckar-A Protein, cckbr Protein, cckra Protein, CCKAR Protein, CCK-A Protein, CCK1-R Protein, CCKRA Protein, AW106902 Protein, Cck-ar Protein, CCK-AR Protein, cholecystokinin A receptor Protein, cholecystokinin A receptor L homeolog Protein, CCKAR Protein, cckar.L Protein, Cckar Protein
- 背景
- This gene encodes a G-protein coupled receptor that binds non-sulfated members of the cholecystokinin (CCK) family of peptide hormones. This receptor is a major physiologic mediator of pancreatic enzyme secretion and smooth muscle contraction of the gallbladder and stomach. In the central and peripheral nervous system this receptor regulates satiety and the release of beta-endorphin and dopamine. [provided by RefSeq, Jul 2008]
- 分子量
- The human full length CCKAR protein has a MW of 47.8kDa
- UniProt
- P32238
- 途径
- Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Feeding Behaviour
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