CCBP2 蛋白
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- 抗原 See all CCBP2 蛋白
- CCBP2 (Chemokine Binding Protein 2 (CCBP2))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human ACKR2 full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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- Discover our top product CCBP2 蛋白
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Chemokine Binding Protein 2 (CCBP2) (AA 315-384) protein (His-IF2DI Tag)
CCBP2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % by SDS-PAGE gel analyses ELISA, WB
Chemokine Binding Protein 2 (CCBP2) (AA 1-384) protein (GST tag)CCBP2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Chemokine Binding Protein 2 (CCBP2) protein (Myc-DYKDDDDK Tag)CCBP2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- CCBP2 (Chemokine Binding Protein 2 (CCBP2))
- 别名
- ACKR2 (CCBP2 产品)
- 别名
- CCBP2 Protein, CCR10 Protein, CCR9 Protein, CMKBR9 Protein, D6 Protein, hD6 Protein, Ccbp2 Protein, LOC733624 Protein, A130091K22Rik Protein, Cmkbr10 Protein, GPR-9-6 Protein, AI464239 Protein, Cmkbr9 Protein, atypical chemokine receptor 2 Protein, atypical chemokine receptor 2-like Protein, chemokine receptor D6 Protein, chemokine (C-C motif) receptor 9 Protein, C-C motif chemokine receptor 9 Protein, ACKR2 Protein, Ackr2 Protein, LOC100219492 Protein, LOC733624 Protein, Ccr9 Protein, CCR9 Protein
- 背景
- This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members, however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes. [provided by RefSeq, Jul 2008]
- 分子量
- The human full length ACKR2 protein has a MW of 43.4kDa
- UniProt
- O00590
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