CCRL1 蛋白
CCRL1
宿主: 人
宿主: Mammalian Cells
Synthetic Nanodisc
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- 抗原 See all CCRL1 蛋白
- CCRL1 (Chemokine (C-C Motif) Receptor-Like 1 (CCRL1))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human ACKR4 full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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- Discover our top product CCRL1 蛋白
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Chemokine (C-C Motif) Receptor-Like 1 (CCRL1) (AA 1-350) protein (GST tag)
CCRL1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- CCRL1 (Chemokine (C-C Motif) Receptor-Like 1 (CCRL1))
- 别名
- ACKR4 (CCRL1 产品)
- 别名
- CC-CKR-11 Protein, CCBP2 Protein, CCR-11 Protein, CCR10 Protein, CCR11 Protein, CCRL1 Protein, CCX CKR Protein, CCX-CKR Protein, CKR-11 Protein, PPR1 Protein, VSHK1 Protein, A630091E18Rik Protein, CCX-CKR1 Protein, Ccrl1 Protein, Cmkbrl1 Protein, atypical chemokine receptor 4 Protein, chemokine (C-C motif) receptor-like 1 Protein, Chemokine receptor-like 1 Protein, chemerin chemokine-like receptor 1 Protein, ACKR4 Protein, Ackr4 Protein, CCRL1 Protein, cml1 Protein, CMKLR1 Protein
- 背景
- The protein encoded by this gene is a member of the G protein-coupled receptor family, and is a receptor for C-C type chemokines. This receptor has been shown to bind dendritic cell- and T cell-activated chemokines including CCL19/ELC, CCL21/SLC, and CCL25/TECK. A pseudogene of this gene is found on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2013]
- 分子量
- The human full length ACKR4 protein has a MW of 39.9kDa
- UniProt
- Q9NPB9
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