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- 抗原 See all CCR4 蛋白
- CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))
- 蛋白类型
- MSP Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human CCR4 full length protein membrane nanoparticles (MNPs)
- 产品特性
- Plasma membrane-coated nanoparticles (MNPs) have been used in various applications, including delivery of therapeutic agents and induction of immune responses et al. Unlike the conventional strategies, MNPs directly leverage intact and natural functions of cell membranes, and show high biocompatibility, specificity, and low side effects. Our optimized MNPs platform for the full-length membrane protein production uses membrane coating technology and a HEK293 based expression platform. The high-purity plasma membrane-coated nanoparticles were produced by extrusion after membrane extraction from the host HEK293 cells containing the overexpressed target proteins.
- Top Product
- Discover our top product CCR4 蛋白
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Chemokine (C-C Motif) Receptor 4 (CCR4) (AA 1-39) protein (Fc Tag)
CCR4 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Chemokine (C-C Motif) Receptor 4 (CCR4) (AA 1-39) protein (mFc Tag)CCR4 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Chemokine (C-C Motif) Receptor 4 (CCR4) proteinCCR4 宿主: 人 宿主: HEK-293 Cells Synthetic Nanodisc
Chemokine (C-C Motif) Receptor 4 (CCR4) protein-VLPCCR4 宿主: 人 宿主: HEK-293 Cells VLP
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- 说明
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Advantages of Membrane Nanoparticles (MNPs):
- High display density of target membrane proteins
- Native structure and orientation of transmembrane protein
- soluble in aqueous solutions for routine biochemical analysis
- Detergent-free purification process
- Strong immunogenicity
- Works for MPs that can´t be produced via VLPs and EXos
- Lack of accurate quantification of the target membrane proteins.
- Need to develop special SPR assayx.
- Cell membranes contain housekeeping proteins that can result in immune response dilution.
- Some membrane proteins can´t be enriched on membrane.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))
- 别名
- CCR4 (CCR4 产品)
- 别名
- CC-CKR-4 Protein, CD194 Protein, CKR4 Protein, CMKBR4 Protein, ChemR13 Protein, HGCN:14099 Protein, K5-5 Protein, Ccr4 Protein, C-C CKR-4 Protein, CHEMR1 Protein, Cmkbr4 Protein, LESTR Protein, Sdf1r Protein, C-C motif chemokine receptor 4 Protein, chemokine (C-C motif) receptor 4 Protein, CCR4 Protein, Ccr4 Protein
- 背景
- The protein belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.
- 分子量
- The human full length CCR4 Protein has a MW of 41.4 kDa
- UniProt
- P51679
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