CCR2
宿主: 人
宿主: Tobacco (Nicotiana tabacum)
Recombinant
>80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
WB, SDS, ELISA
限制
仅限研究用
状态
Lyophilized
缓冲液
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
储存条件
-20 °C,-80 °C
储存方法
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Enables C-C chemokine binding activity and C-C chemokine receptor activity. Involved in several processes, including leukocyte migration, positive regulation of cell migration, and regulation of cytokine production. Acts upstream of or within several processes, including cellular defense response, monocyte chemotaxis, and neutrophil clearance. Located in external side of plasma membrane. Is expressed in several structures, including alimentary system, brain, genitourinary system, hemolymphoid system gland, and liver and biliary system. Used to study Coronavirus infectious disease and age related macular degeneration. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease, aggressive periodontitis, coronary artery disease (multiple), glucose metabolism disease (multiple), and uveitis (multiple). Orthologous to human CCR2 (C-C motif chemokine receptor 2). [provided by Alliance of Genome Resources, Apr 2022]
分子量
predicted molecular mass of 32.3 kDa after removal of the signal peptide. The apparent molecular mass of mCCR2-hFc is 35-55 kDa due to glycosylation.