CASR 蛋白
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- 抗原 See all CASR 蛋白
- CASR (Calcium-Sensing Receptor (CASR))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human CASR full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product CASR 蛋白
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Calcium-Sensing Receptor (CASR) (AA 21-120) protein (GST tag)
CASR 宿主: 人 宿主: 小麦胚 Recombinant WB, AP, AA, ELISA
Calcium-Sensing Receptor (CASR) (AA 21-130) protein (GST tag)CASR 宿主: 人 宿主: 小麦胚 Recombinant WB, AP, AA, ELISA
Calcium-Sensing Receptor (CASR) (AA 20-612), (Extracellular) protein (GST tag)CASR 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
Calcium-Sensing Receptor (CASR) (AA 20-612) protein (His tag)CASR 宿主: 人 宿主: 酵母菌 Recombinant > 90 % SDS
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- CASR (Calcium-Sensing Receptor (CASR))
- 别名
- CASR (CASR 产品)
- 别名
- CAR Protein, EIG8 Protein, FHH Protein, FIH Protein, GPRC2A Protein, HHC Protein, HHC1 Protein, HYPOC1 Protein, NSHPT Protein, PCAR1 Protein, CaR Protein, Gprc2a Protein, gprc2a Protein, xV2R F-1 Protein, CASR Protein, calcium sensing receptor Protein, calcium-sensing receptor Protein, calcium-sensing receptor L homeolog Protein, CASR Protein, Casr Protein, casr.L Protein
- 背景
- The protein encoded by this gene is a plasma membrane G protein-coupled receptor that senses small changes in circulating calcium concentration. The encoded protein couples this information to intracellular signaling pathways that modify parathyroid hormone secretion or renal cation handling, and thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene are a cause of familial hypocalciuric hypercalcemia, neonatal severe hyperparathyroidism, and autosomal dominant hypocalcemia. [provided by RefSeq, Aug 2017]
- 分子量
- The human full length CASR protein has a MW of 120.7kDa
- UniProt
- P41180
- 途径
- Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis
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